Table 3.

Univariate and multivariable Cox regression analyses

	Univariate analyses			Coefficient	Multivariate analyses
	HR	95% CI	P-value		HR	95% CI	P-value
Age (≥ 61 years vs. < 61 years)	1.347	0.950–1.910	0.094
Gender (male vs. female)	0.817	0.573–1.164	0.264
Grade (3–4 vs. 1–2)	1.118	0.780–1.603	0.545
AJCC PT (3–4 vs. 1–2)	2.548	1.794–3.617	< 0.001
AJCC PN (1–2 vs. 0)	1.516	1.052–2.185	0.026
AJCC PM (1–2 vs. 0)	1.674	1.162–2.413	0.006	0.803	2.231	1.269–3.924	0.005
AJCC stage (3–4 vs. 1–2)	2.442	1.685–3.540	< 0.001
Child pugh (2–3 vs. 1)	1.614	0.796–3.270	0.184
Prognostic nomogram (high vs. low)	4.162	2.798–6.191	< 0.001	1.591	4.909	2.751–8.762	< 0.001

AJCC The American Joint Committee on Cancer, HR hazard ratio, CI confidence interval