Table 1.
Expression levels of 13 features regarding 9 immune checkpoint markers in nasopharyngeal carcinoma
| No. of NPC Patients (%) with Expression Above the Cutoff Value | |||||
|---|---|---|---|---|---|
| Marker | Median | > 1% | > 5% | > 25% | > 50% |
| TAIC expression | |||||
| PD-L1 | 12.97 | 201 (97) | 151 (73) | 59 (28) | 16 (8) |
| B7-H3 | 26.13 | 196 (94) | 175 (84) | 105 (50) | 50 (24) |
| B7-H4 | 22.06 | 205 (99) | 195 (94) | 90 (43) | 21 (10) |
| IDO-1 | 20.75 | 206 (99) | 187 (90) | 83 (40) | 14 (7) |
| LAG3 | 5.55 | 197 (95) | 109 (52) | 15 (7) | 5 (2) |
| VISTA | 12.46 | 205 (99) | 169 (81) | 30 (14) | 3 (1) |
| TIM3 | 2.75 | 183 (88) | 62 (30) | 0 (0) | 0 (0) |
| ICOS | 26.21 | 207 (100) | 204 (98) | 111 (53) | 9 (4) |
| OX40 | 19.95 | 208 (100) | 192 (92) | 80 (38) | 24 (12) |
| TC expression | |||||
| PD-L1 | 10.44 | 191 (92) | 136 (65) | 49 (24) | 22 (11) |
| B7-H3 | 7.01 | 165 (79) | 115 (55) | 50 (24) | 19 (9) |
| B7-H4 | 13.41 | 200 (96) | 162 (78) | 57 (27) | 13 (6) |
| IDO-1 | 7.66 | 195 (94) | 131 (63) | 23 (11) | 6 (3) |
Abbreviations: TC tumour cell, TAIC tumour-associated immune cell