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. 2019 Nov 13;12:164. doi: 10.1186/s12920-019-0586-4

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — The genomic and epigenomic landscapes of primary hepatocellular carcinomas and PVTTs. a Copy number variations in primary tumor and PVTTs. b Focal copy number (CN) alterations detected by GISTIC2 (only the primary tumors were shown). c The DNA methylation levels in CpG islands and in whole genomes