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. 2019 Nov 14;7:301. doi: 10.1186/s40425-019-0776-9

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Survival curves of myeloma bearing Balb/c recipient mice treated by irradiation, Auto-BMT and then allogeneic or autologous lymphocyte infusion. The presented results represent the average of two independent experiments. On day 10 and/or day 17 after Auto-BMT, recipient mice were injected i.v. with naïve or activated B10.D2 / Balb/c Vβ 2, 3 and 8.3 T cells. Recipient mice were sacrificed when severe GvHD symptoms, myeloma symptoms or apathy were present. Statistical significance between survival curves was determined using the Log-Rank test. MM-Auto-BMT versus MM-Auto-BMT + Auto activated vβ 2, 3, 8.3 (× 1), *p < 0.0001; MM-Auto-BMT versus MM-Auto-BMT + Allo naive vβ 2, 3, 8.3 (× 1), **p = 0.0001