Fig. 2.

Absolute counts of circulating myeloid-derived suppressors in acute and chronic sepsis. Cells with the surface markers CD33⁺CD11b⁺HLA-DR^−/low were identified on the flow cytometer, and absolute counts ([total white blood cell count (cells/ml) × percent CD33⁺CD11b⁺HLA-DR^low/−]/100) were determined for septic patients. The mean values of absolute counts are reported for patients at various time points beginning 24 h (n = 241) after the initial infectious onset and on days 4 (n = 211), 7 (n = 166), 14 (n = 100), 21 (n = 59), 28 (n = 38), 36 (n = 28), and 42 (n = 18) in patients meeting the Sepsis-3 criteria