Table 2.
Genotype Frequencies of Polymorphism CYP1А1, CYP2E1, GSTP1 genes in the studied groups
| SNPs | Exp1 (%) |
P value | Exp2 (%) |
P value | VS Unexp (%) |
|---|---|---|---|---|---|
| 1.CYP1А1 rs1048943 | |||||
| AA | 67 (59) | 68 (70) | 44 (33) | ||
| AG | 36 (32) | 0.0002* | 24 (25) | 0.0002* | 73 (55) |
| GG | 11 (9) | 5 (5) | 15 (12) | ||
| 2. rs4646421 | |||||
| AA | 29 (25) | 27 (23) | 33 (25) | ||
| AG | 47 (41) | 0.97 | 47 (41) | 0.92 | 55 (41) |
| GG | 39 (34) | 42 (36) | 45 (34) | ||
| 3. CYP2Е1 rs2070676 | |||||
| CC | 85 (76) | 86 (69) | 99 (79) | ||
| CG | 22 (20) | 0.89 | 33 (26) | 0.17 | 22 (18) |
| GG | 4 (4) | 6 (5) | 4 (3) | ||
| 4. rs3813867 | |||||
| CC | 17 (15) | 21 (17) | 8 (5) | ||
| CG | 45 (39) | 0.02 | 47 (38) | 0.004 | 55 (37) |
| GG | 53 (46) | 55 (45) | 86 (58) | ||
| 5. GSTP1 rs1695 | |||||
| AA | 84 (74) | 82 (77) | 79 (64) | ||
| AG | 24 (21) | 0.23 | 20 (19) | 0.09 | 35 (29) |
| GG | 5 (5) | 4 (4) | 9 (7) | ||
* p < 0.003 with correction for the multiplicity of comparisons
SNP single nucleotide polymorphism