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. 2019 Nov 13;17:89. doi: 10.1186/s12915-019-0709-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — ETS1 as an important downstream factor of cell-cell crosstalk regulating cardiac lineage commitment. a–c Gene set enrichment analysis (GSEA) shows significant enrichment of three essential pathways potentially activating MEF2C and ETS1 at day 5 in cardiac progenitors. d Heat map showing the expression of previously reported cardiac TFs and ETS1 at day 5 in cardiac progenitor population