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. 2019 Nov 7;10:1106. doi: 10.3389/fgene.2019.01106

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Copyright © 2019 Yi, You and Guo

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The performance of Molecular Association Network (MAN)–High-Order Proximity preserved Embedding (HOPE) for predicting miRNA-disease associations. (A) five-fold cross-validation performance using behavior (network embedding) feature and attribute feature of nodes; (B) five-fold cross-validation performance using only attribute feature; (C) five-fold cross-validation performance using only behavior feature; (D) comparison of performance of attribute feature, behavior feature, and combined use for predicting miRNA-disease associations.