Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Nov 7;12:267. doi: 10.3389/fnmol.2019.00267

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Prestori, Mapelli and D’Angelo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Developmental origin of cerebellar GABAergic neurons. Ptf1-a-positive progenitors in the ventricular zone (VZ) generate the entire repertory of GABAergic projection neurons and interneurons through different neurogenic strategies. While projection neurons proliferate and become specified within the VZ, cortical interneurons derive from precursors that originate in the VZ but continue their neurogenic activity in the pWM or dWM, where they acquire mature identities under the influence of specific extracellular cues. Afterward, the interneurons move to their final destination through the folial white matter (fWM). pWM, prospective white matter; dWM, deep white matter; fWM, folial white matter; DCN, deep cerebellar nuclei; PC, Purkinje cell; BC, basket cell; SC, stellate cell; LC, Lugaro cell; GoC, Golgi cell. Modified from Leto et al. (2012).