Table 5.
Hazard ratios for experiencing an adverse clinical event during 12-month follow-up.
| HR | 95% CI | p | |
|---|---|---|---|
| Age, per year | 0.98 | 0.94–1.02 | 0.294 |
| Male gender | 0.7 | 0.2–1.8 | 0.420 |
| Ischemic postconditioning | 0.5 | 0.2–1.3 | 0.179 |
| Time, symptoms to PCI (ln), per SD | 1.1 | 0.7–1.7 | 0.737 |
| Peak troponin T (ln), per SD | 1.7 | 1.0–2.8 | 0.037 |
| Peak CRP (ln), per SD | 3.1 | 1.7–5.5 | <0.001 |
| Baseline NT-proBNP (ln), per SD | 1.1 | 0.7–1.8 | 0.650 |
| TIMI risk score, per point | 1.3 | 1.1–1.6 | 0.016 |
| High dsDNA before PCI | 2.9 | 1.0–8.0 | 0.043 |
| Adjusted for peak troponin T | 2.6 | 0.9–7.3 | 0.065 |
| Adjusted for peak CRP | 2.4 | 0.8–6.8 | 0.105 |
| Adjusted for TIMI risk score | 2.7 | 1.0–7.6 | 0.057 |
| High dsDNA on day 1 | 5.9 | 1.7–20.3 | 0.005 |
| Adjusted for male gender | 6.7 | 1.9–23.2 | 0.003 |
| Adjusted for peak troponin T | 5.1 | 1.4–18.4 | 0.012 |
| Adjusted for peak CRP | 3.5 | 1.0–12.5 | 0.058 |
| Adjusted for TIMI risk score | 5.2 | 1.5–18.1 | 0.009 |
High dsDNA is defined as >median (before PCI: >452 ng/ml; day 1: >367 ng/ml). Adverse clinical event is defined as a composite of all-cause mortality, myocardial infarction, unscheduled revascularization ≥ 3 months after the index infarction, rehospitalization for heart failure, or stroke. CI: confidence interval. CRP: C-reactive protein. HR: hazard ratio. PCI: percutaneous coronary intervention. SD: standard deviation. TIMI: thrombolysis in myocardial infarction.