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Overall schematic. Hyperoxia increases SNAI1 expression in vitro, but females show decreased expression in vivo. miR-30a decreases Snai1 expression, and females show higher expression. HIF-1α increases both the miR-30a and Snai1 expressions, but HIF-1α-mediated miR-30a expression in females keeps the Snai1 expression in check upon exposure to hyperoxia.
