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Inhibitory concentrations of compound 1 at 24 hours.
| Cell types | Concentrations of compound 1 (μM) | ||
|---|---|---|---|
| IC10 | IC20 | IC50 | |
| MDA-MB-231 | 57.1 ± 3.5 | 84.8 ± 2.8 | 232.7 ± 3.9∗∗∗∗ |
| MCF-7 | 22.8 ± 3.7 | 45.7 ± 4.8 | 88.3 ± 5.4 |
| NIH3T3 | — | — | >200 |
| PBMCs | — | — | >200 |
∗∗∗∗ p < 0.0001, IC50 of compound 1-treated MDA-MB-231 compared with compound 1-treated MCF-7 at 24 hours.
