Table 2.
Univariate and multivariate linear regression associating baseline variables with lymphocyte nadirs during radiation treatment.
| Variable | Regression coefficient | 95% CI | p value |
|---|---|---|---|
| Univariate analysis | |||
| Gender | −0.136 | −0.294 to 0.022 | 0.090 |
| Age | 0.006 | 0.001 to 0.011 | 0.025 |
| KPS | 0.003 | −0.011 to 0.017 | 0.681 |
| Child-Pugh | −0.073 | −0.141 to −0.004 | 0.037 |
| BCLC stage | −0.1 | −0.179 to −0.02 | 0.014 |
| Tumor thrombus (yes/no) | −0.169 | −0.318 to −0.021 | 0.026 |
| LNM (yes/no) | −0.186 | −0.368 to −0.004 | 0.045 |
| TACE (yes/no) | −0.015 | −0.138 to 0.107 | 0.805 |
| RFA (yes/no) | 0.027 | −0.177 to 0.231 | 0.795 |
| Tumor size (cm) | −0.019 | −0.035 to −0.004 | 0.015 |
| BED | 0.007 | 0.003 to 0.012 | 0.010 |
| Fractions | −0.016 | −0.023 to −0.009 | <0.001 |
| Log10GTV | −0.205 | −0.238 to −0.127 | <0.001 |
|
| |||
| Multivariate analysis | |||
| Fractions | −0.029 | −0.046 to −0.012 | 0.001 |
| Log10GTV | −0.195 | −0.291 to −0.099 | <0.001 |
CI = confidence interval.