Figure 7.
Pericoronary fat radiomic profile in acute myocardial infarction. (A) Tukey box-plot of FRP values in patients scanned within 96 h of acute myocardial infarction and matched controls undergoing clinical coronary CT angiography for suspected stable coronary artery disease (n = 44 per group). (B) FRP and perivascular Fat Attenuation Index in acute myocardial infarction patients scanned within 96 hours of admission and 6 months later (n = 16 per group). (C) In a subgroup of patients with ST-elevation myocardial infarction (STEMI) at baseline, Fat Attenuation Index changes were particularly pronounced in the region directly adjacent to the culprit lesion (n = 10). (D) Change in Fat Attenuation Index-associated inflammatory burden, defined as the area under the curve of Fat Attenuation Index measured along a given culprit lesion within 96 h of an acute ST-segment elevation myocardial infarction (STEMI) and 6 months later. AMI, acute myocardial infarction; AU, arbitrary units; CAD, coronary artery disease; FAI, Fat Attenuation Index; HU, Hounsfield Units; STEMI, ST-segment elevation myocardial infarction. P-values derived from Mann–Whitney U test (A), Wilcoxon-signed rank test (B, D) and two-way repeated measures analysis of variance with timepoint/distance interaction (C).
