Table I.
Level | Microscopic findings |
---|---|
0 | No mucosal changes |
1 | Despite Grunhagen changes in subepithelial region, villous structures are preserved and no cellular damage or inflammation |
2 | Lysis at cellular level, increase in gap between villous structures, and formation of Grunhagen in subepithelial region |
3 | Destruction of free villous structures, dilation at capillary level and inflammation at cellular level |
4 | Inflamed cells, necrotic material, bleeding, and ulceration due to near-total destruction of the villous structures |
5 | No visible structure other than amorphous material in the submucosal tissue and the entirely destroyed mucous membrane |