Table 2.
Clinical characteristics | Variable | No. of patients | OGDHL expression | χ 2 | P value | |||
---|---|---|---|---|---|---|---|---|
High | % | Low | % | |||||
Age | <55 | 117 | 74 | 27.41 | 43 | 42.16 | 6.802 | 0.009 |
≥55 | 255 | 196 | 72.59 | 59 | 57.84 | |||
| ||||||||
Gender | Female | 121 | 86 | 31.85 | 35 | 33.98 | 0.072 | 0.788 |
Male | 252 | 184 | 68.15 | 68 | 66.02 | |||
| ||||||||
Histological type | Fibrolamellar carcinoma | 3 | 3 | 1.11 | 0 | 0 | 1.809 | 0.617 |
Hepatocellular carcinoma | 363 | 261 | 96.67 | 102 | 99.03 | |||
Hepatocholangiocarcinoma (mixed) | 7 | 6 | 2.22 | 1 | 0.97 | |||
| ||||||||
Histologic grade | G1 | 55 | 41 | 15.47 | 14 | 13.59 | 25.673 | 0.000 |
G2 | 178 | 147 | 55.47 | 31 | 30.1 | |||
G3 | 123 | 69 | 26.04 | 54 | 52.43 | |||
G4 | 12 | 8 | 3.02 | 4 | 3.88 | |||
| ||||||||
Stage | I | 172 | 135 | 54 | 37 | 37.37 | 10.116 | 0.015 |
II | 87 | 60 | 24 | 27 | 27.27 | |||
III | 85 | 51 | 20.4 | 34 | 34.34 | |||
IV | 5 | 4 | 1.6 | 1 | 1.01 | |||
| ||||||||
T classification | T1 | 182 | 144 | 53.73 | 38 | 36.89 | 10.765 | 0.020 |
T2 | 95 | 64 | 23.88 | 31 | 30.1 | |||
T3 | 80 | 49 | 18.28 | 31 | 30.1 | |||
T4 | 13 | 10 | 3.73 | 3 | 2.91 | |||
TX | 1 | 1 | 0.37 | 0 | 0 | |||
| ||||||||
N classification | N0 | 253 | 178 | 65.93 | 75 | 73.53 | 3.519 | 0.149 |
N1 | 4 | 2 | 0.74 | 2 | 1.96 | |||
NX | 115 | 90 | 33.33 | 25 | 24.51 | |||
| ||||||||
M classification | M0 | 267 | 186 | 68.89 | 81 | 78.64 | 3.523 | 0.156 |
M1 | 4 | 3 | 1.11 | 1 | 0.97 | |||
MX | 102 | 81 | 30 | 21 | 20.39 | |||
| ||||||||
Radiation therapy | No | 340 | 245 | 97.22 | 95 | 98.96 | 0.320 | 0.572 |
Yes | 8 | 7 | 2.78 | 1 | 1.04 | |||
| ||||||||
Residual tumor | R0 | 326 | 239 | 90.53 | 87 | 85.29 | 4.018 | 0.245 |
R1 | 17 | 12 | 4.55 | 5 | 4.9 | |||
R2 | 1 | 1 | 0.38 | 0 | 0 | |||
RX | 22 | 12 | 4.55 | 10 | 9.8 | |||
| ||||||||
Vital status | Deceased | 130 | 85 | 31.48 | 45 | 43.69 | 4.371 | 0.037 |
Living | 243 | 185 | 68.52 | 58 | 56.31 |