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. 2019 Nov 7;10:1310. doi: 10.3389/fphar.2019.01310

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Copyright © 2019 Shen, Yuan, Guo, Li, Li and Pu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Chemical structural formulas of four ligands (ligand 1 binds to conformational a, ligand 2 binds to conformational b, ligand 3 binds to conformational d, ligand 4 binds to conformational g).