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. 2019 Apr 3;8(4):136–148. doi: 10.1089/wound.2018.0819

Table 3.

Hurdle effects of pulsed electric field and antibiotics on S. epidermidis inactivation

Ec/p-Value PEF Alone Dil 1 Dil 2 Dil 3 Dil 4 Dil 5 PEF+Dil 1 PEF+Dil 2 PEF+Dil 3 PEF+Dil 4 PEF+Dil 5
PEF alone 378.41 V/mm/p = 0.000                    
Dil 1 p = 0.000 ∞*                  
Dil 2 p = 0.000 — ∞*                
Dil 3 p = 0.000 — — ∞*              
Dil 4 p = 0.000 — — — ∞*            
Dil 5 p = 0.000 — — — — ∞*          
PEF+Dil 1 p = 0.020 p = 0.000 p = 0.000 p = 0.000 p = 0.000 p = 0.000 348.51 V/mm        
PEF+Dil 2 p = 0.010 p = 0.000 p = 0.000 p = 0.000 p = 0.000 p = 0.000 p = 0.438 350.12 V/mm      
PEF+Dil 3 p = 0.001 p = 0.000 p = 0.000 p = 0.000 p = 0.000 p = 0.000 p = 0.025 p = 0.033 325.67 V/mm    
PEF+Dil 4 p = 0.003 p = 0.000 p = 0.000 p = 0.000 p = 0.000 p = 0.000 p = 0.013 p = 0.039 p = 0.226 334.04 V/mm  
PEF+Dil 5 p = 0.006 p = 0.000 p = 0.000 p = 0.000 p = 0.000 p = 0.000 p = 0.039 p = 0.024 p = 0.355 p = 0.281 331.10 V/mm

PEF parameters: pulse duration = 60 μs; interval between pulses = 350 ms; number of pulses = 200; n = 36. Dil 1: Pen G 5,000 units/mL, Strep 5 mg/mL, Nys 625 units/mL; Dil 2: Pen G 2,000 units/mL, Strep 2 mg/mL, Nys 250 units/mL; Dil 3: Pen G 1,000 units/mL, Strep 1 mg/mL, Nys 125 units/mL; Dil 4: Pen G 666.7 units/mL, Strep 0.67 mg/mL, Nys 83.3 units/mL; Dil 5: Pen G 500 units/mL, Strep 0.5 mg/mL, Nys 62.5 units/mL.

*

Equivalent to Ec.

**

∞ no delay effect.

—, no value.

Gray shading shows no significant difference.