Skip to main content
. 2019 May 3;8(5):208–219. doi: 10.1089/wound.2018.0864

Figure 2.

Figure 2.

Assessment of the skin barrier. (a) Shows the increase in hydration, which is much greater in the treatment arm compared to the control and was significant in weeks 4–12 (p < 0.05). (b) (TEWL) results (which correlate with hydration). (c) IHC staining for hyaluronic acid. (d) The intensity of staining over sequential time points with p < 0.05 at weeks 4 (p = 0.014), 12 (p = 0.039), and 16 (p = 0.042), and in qRT-PCR (e) at week 16 (p = 0.049) (significant results marked with a star). There were 40 subjects in the group for the shortest time period (4 weeks); 10 subjects exited at this (and every subsequent) time point, leaving 30 subjects in the week 8 group, 20 subjects in the week 12 group, and finally, 10 subjects in the week 16 group. Yellow = normal skin (day 0). IHC, immunohistochemistry; qRT-PCR, quantitative real-time PCR.