TABLE 3.

Effect of allopurinol on haemodynamics, endothelial function and vascular stiffness

Change in measured parameter	Placebo	Allopurinol	P value
24 h systolic (mmHg)	1.2 ± 8.0	0.61 ± 8.0	0.799
24 h diastolic (mmHg)	−0.04 ± 5.40	0.67 ± 4.76	0.634
Daytime systolic (mmHg)	1.57 ± 7.30	−0.94 ± 8.05	0.205
Daytime diastolic (mmHg)	0.07 ± 5.41	0.34 ± 5.72	0.846
FMD (%)	−0.23 ± 3.65	0.14 ± 4.12	0.718
AIx	−0.30 ± 13.46	0.06 ± 12.41	0.913
PWV (m/s)	−0.09 ± 1.12	−0.25 ± 1.07	0.581

AIx, augmentation index; FMD, flow-mediated dilatation; PWV, pulse wave velocity.