TABLE 3.

Comparison between losartan and hydrochlorothiazide vs. losartan and amlodipine group in intraindividual smoothness index of brachial and central SBP and vascular parameters

	Losartan and HCTZ (n = 72)	Losartan and amlodipine (n = 70)	P
Smoothness index for brachial SBP	0.39 ± 0.57	0.66 ± 0.78	0.0151
Mean hourly reduction (mmHg)	6.33 ± 10.02	10.4 ± 12.5	0.0311
SD of hourly reduction (mmHg)	20.2 ± 6.7	17.0 ± 5.2	0.002
Smoothness index for central SBP	0.40 ± 0.57	0.65 ± 0.74	0.022
Mean hourly reduction (mmHg)	6.15 ± 9.03	9.79 ± 11.45	0.0362
SD of hourly reduction (mmHg)	18.59 ± 5.67	16.0 ± 4.8	0.0036

AIx, augmentation index; cfPWV, carotid femoral pulse wave velocity; HCTZ, dihydrochlorothiazide; PPA, pulse pressure amplification; SD, standard deviation.