TABLE 5.
Multivariable regression model for the factors associated with smoothness index
| Variable | Beta | Model Rsq | Pa |
| Model 1 | |||
| Smoothness index of brachial SBP | |||
| LA group (reference: LH group) | 0.2698 | 0.0274 | 0.0148 |
| Age | 0.0097 | 0.0365 | 0.0327 |
| Smoothness index of central SBP | |||
| LA group (reference: LH group) | 0.2526 | 0.0363 | 0.0200 |
| Model 2 | |||
| Smoothness index of brachial SBP | |||
| Reduction of 24-h ambulatory cfPWV | 1.5904 | 0.7878 | <0.0001 |
| Smoothness index of central SBP | |||
| Reduction of 24-h ambulatory cfPWV | 1.5476 | 0.8253 | <0.0001 |
| Increase in mean pulse pressure amplification | 0.8510 | 0.8323 | 0.0243 |
Model 1 includes covariates of baseline age, sex, smoking or drinking status, height, waist circumference and treatment group. Model 2 additionally includes clinic brachial SBP at baseline and week 20, the changes in ACR, fasting blood glucose, uric acid, mean ambulatory heart rate, mean APPA, mean AAIx75, mean AcfPWV, daytime AcfPWV and night-time AcfPWV in addition to the model 1.
LA, losartan and amlodipine combination; LH, losartan and dihydrochlorothiazide combination.
aStepwise multivariate regression analysis.