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. Author manuscript; available in PMC: 2019 Nov 14.
Published in final edited form as: ACS Chem Biol. 2018 Oct 30;13(11):3043–3048. doi: 10.1021/acschembio.8b00429

Figure 3: Synthetic standards of potential methylation products.

Figure 3:

Triacetic acid lactone (1) and variously methylated derivatives 3–5 were obtained by published procedures16, 17 or from commercial sources. These were further elaborated to tetraketides 6, 7, 10, 12–15 as detailed in the Supplementary Information.