TABLE 1.
Wild type | GSK3α KO | sAC KO | ||||
---|---|---|---|---|---|---|
Inhibitors | Caput | Cauda | Caput | Cauda | Caput | Cauda |
PPP1R2 | Not bound | Bound | Not bound | Bound | Not bound | Bound |
PPP1R7 | Not bound | Bound | Not bound | Not bound | Not bound | Not bound |
PPP1R11 | Bound | Bound | Bound | Bound | Bound | Bound |
Note. PPP1R2, PPP1R7, and PPP1R11 are bound to PP1y2 in caudal epididymis whereas PPP1R7, PPP1R2 remains unbound in caput epididymis. Caudal sperm from Gsk3a KO and sAC ko behave partially like wild-type caput sperm.