Table 1. Drug lists for the detection of potential DDIs.
Drug class | Drug groups | Drug lists |
---|---|---|
Cardiac drugs | Beta blockers | 1. Atenolol 2. Bisoprolol 3. Carvedilol 4. Esmolol 5. Metoprolol 6. Nebivolol 7. Propranolol |
Antianginal agents | 8. Ranolazine 9. Trimetazidine |
|
Vasodilating agents | Phosphodiesterase inhibitors | 10. Dipyridamole |
Arteriolar dilators | 11. Hydralazine 12. Minoxidil |
|
Prostacyclin analogues | 13. Iloprost 14. Beraprost |
|
Nitrates | 15. Isosorbide dinitrate 16. Isosorbide mononitrate 17. Nitroglycerin |
|
Phosphodiesterase-5 inhibitors | 18. Sildenafil | |
Peripheral vasodilators and related agents | Peripheral vasodilator agents | 19. Nicergoline |
Xanthine derivatives | 20. Pentoxifylline | |
Antiplatelets | Cyclooxygenase inhibitors | 21. Acetylsalicylic acid |
Phospholipase-3 inhibitors | 22. Cilostazol 23. Omega-3-acid ethyl ester |
|
Antilipemic agents | Chelating agents | 24. Cholestyramine |
Fibrates | 25. Fenofibrate 26. Gemfibrozil |
|
HMG-CoA reductase inhibitors | 27. Atorvastatin 28. Pitavastatin 29. Pravastatin 30. Rosuvastatin 31. Simvastatin |
|
Nicotinic acid | 32. Nicotinic acid | |
Selective cholesterol absorption inhibitors | 33. Ezetimibe | |
PCSK9 inhibitors | 34. Evolocumab | |
Antihypertensive drugs | Angiotensin converting enzyme inhibitors | 35. Captopril 36. Enalapril 37. Imidapril 38. Perindopril 39. Quinapril 40. Ramipril |
Angiotensin receptor blockers | 41. Azilsartan 42. Candesartan 43. Irbesartan 44. Losartan 45. Olmesartan 46. Telmisartan 47. Valsartan |
|
Neprilysin inhibitors | 48. Sacubitril valsartan sodium salt complex | |
Thiazide and related diuretics | 49. Hydrochlorothiazide 50. Indapamide 51. Chlorthalodine |
|
Alpha-2 adrenergic receptors | 52. Methyldopa 53. Clonidine |
|
Alpha adrenergic antagonists | 54. Doxazosin 55. Prazosin |
|
Calcium channel blockers | 56. Amlodipine 57. Diltiazem 58. Felodipine 59. Lercanidipine 60. Manidipine 61. Nifedipine 62. Nimodipine 63. Verapamil |
|
Direct renin inhibitors | 64. Aliskiren | |
Endothelin-1 receptor antagonists | 65. Bosentan 66. Macitentan |
|
Diuretics | Diuretics loop diuretics | 67. Furosemide |
Carbonic anhydrase inhibitors | 68. Acetazolamide | |
Osmotic diuretics | 69. Mannitol 70. Glycerin |
|
Potassium-sparing diuretics | 71. Amiloride 72. Spironolactone |
|
Antidiabetic drugs | Alpha-glucosidase inhibitors | 73. Acarbose |
Biguanides | 74. Metformin | |
Dipeptidyl peptidase-4 inhibitors | 75. Linagliptin | |
Glucagon-like peptide-1 receptor agonists | 76. Liraglutide 77. Dulaglutide |
|
Meglitinide analogs | 78. Repaglinide | |
Sodium glucose co-transporter type 2 inhibitors | 79. Dapagliflozin 80. Empagliflozin |
|
Sulfonylureas | 81. Glimepiride 82. Glipizide |
|
Thiazolidinediones | 83. Pioglitazone | |
Insulins | 84. Insulin |