Skip to main content
. 2019 Nov 14;14(11):e0225063. doi: 10.1371/journal.pone.0225063

Fig 5. Protective immunization regimens induce lower HA-specific B cells responses post-boost immunizations.

Fig 5

Frequencies of HA-binding cells among GC B cell (A) and non-GC B cell (B) populations in iliac lymph nodes as measured at day 25 (4 days post-boost immunization) in mice (n = 8 per time-point per cohort) vaccinated with the alum-adjuvanted Mini-HA UFV#4900, UFV#4650, UFV#4157 antigens (30 μg), FL HA FL H1#2316, at an equimolar dose of 60 μg, or PBS. Each symbol represents one animal while group means are indicated by a horizontal bar. Statistical comparisons are made by comparing group means of the miniHA vaccinated animals in a one-way ANOVA, corrected for multiple comparisons using Tukey’s statistical hypothesis testing.