Table IV.
Results of multiple regression analysis of factors associated with an abnormal brain MRI and neurosurgical intervention in the 75 infants with bacterial meningitis who had MRI performed
| Brain MRI | Neurosurgical intervention after MRI | |||||||
|---|---|---|---|---|---|---|---|---|
| Abnormal | Normal | OR | Neurosurgery | No neurosurgery | OR | |||
| MRI | MRI | P value | (95% CI) | after MRI | after MRI | P value | (95% CI) | |
| No. of infants (n = 75) | 61 | 14 | - | - | 17 | 58 | - | - |
| Late seizures (n = 38) | 37 (97%) | 1 (3%) | .0001 | 20 (2.4–163) | 11 (29%) | 27 (71%) | .18 | 2.1 (0.68–6.5) |
| New onset of fever (n = 10) | 8 (80%) | 2 (20%) | 1 | 0.8 (0.1620134.5) | 3 (30%) | 7 (70%) | .55 | 1.5 (0.35–6.8) |
| Fever for ≥4 d (n = 18) | 15 (83%) | 3 (17%) | .68 | 1.1 (0.2–4.86) | 6 (33%) | 12 (67%) | .21 | 2.0 (0.64–6.8) |
| Abnormal neurologic examination (n = 25) | 24 (96%) | 1 (4%) | .01 | 8.4 (1.0–68.7) | 8 (32%) | 17 (68%) | .17 | 2.1 (0.7–6.49) |
| Positive CSF culture >48 h (n = 18) | 16 (89%) | 2 (11%) | .16 | 2.1 (0.4–10.5) | 8 (44%) | 10 (56%) | .01 | 4.2 (1.3–13.7) |