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. Author manuscript; available in PMC: 2019 Nov 14.
Published in final edited form as: Oral Oncol. 2019 Mar 4;91:69–78. doi: 10.1016/j.oraloncology.2019.02.026

Table 1.

PTEN/PIK3CA status by treatment arm, E5397 (among patients with specimens available for marker analysis).

Treatment Arm
Total
Cetuximab
Placebo
N % N % N %
PIK3CA*
 Mutant 1 4 1 4 2 4
 Wild-type 25 96 25 96 50 96
 Unknown 1 1 2
PTEN+
 Null 11 35 12 33 23 34
 Positive 20 65 24 67 44 66
PTEN/PIK3CA&
 PTEN null/PIK3CA mut 12 35 13 33 25 34
 PTEN pos/PIK3CA WT 22 65 26 67 48 66
*

Fifty four specimens analyzed for PIK3CA.

+

Sixty-seven specimens analyzed for PTEN.

&

Seventy-four specimens in total across PIK3Ca and PTEN analysis.