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. 2019 Nov 14;14(11):e0225260. doi: 10.1371/journal.pone.0225260

Table 1. GOT2-carrying nude mice were treated according to the presented schedules with 177Lu-octreotate (Lu), gemcitabine (Gem) and/or external beam radiotherapy (EBRT), or left untreated as control animals.

Administered amount:
Lu (MBq), Gem (mg/kg) or EBRT (Gy)
Group T (d) Day 0 Day 3 Day 7 Day 10 Day 13 n F (d)
Lu 96 10 0 0 0 0 5 16
Gem high 96 125 125 125 60 60 5 16
Lu + Gem high 96 10+125 0+125 0+125 0+60 0+60 5 16
EBRT 62 5 0 0 0 0 5 44
Gem low 137 60 60 60 60 60 10 44
EBRT + Gem low 62 5+60 0+60 0+60 0+60 0+60 6 58
Untreated control 145 - - - - - 12 30

T, median time between transplantation and treatment start; n, number of animals in each group; F, follow-up time.