| A.Upregulated |
| Category |
Term/gene function |
P-value |
Count |
| BP |
GO:0007018 microtubule-based movement |
5.53 × 10−9
|
9 |
| BP |
GO:0032467 positive regulation of cytokinesis |
1.10 × 10−5
|
5 |
| BP |
GO:0007059 chromosome segregation |
1.84 × 10−4
|
5 |
| BP |
GO:0000281 mitotic cytokinesis |
3.22 × 10−4
|
4 |
| BP |
GO:0090307 mitotic spindle assembly |
5.47 × 10−4
|
4 |
| BP |
GO:0007267 cell-cell signaling |
8.26 × 10−3
|
4 |
| CC |
GO:0005737 cytoplasm |
9.72 × 10−3
|
27 |
| CC |
GO:0005634 nucleus |
7.08 × 10−3
|
26 |
| CC |
GO:0005654 nucleoplasm |
2.73 × 10−3
|
18 |
| CC |
GO:0016020 membrane |
4.34 × 10−2
|
11 |
| CC |
GO:0030496 midbody |
4.41 × 10−8
|
9 |
| CC |
GO:0005871 kinesin complex |
1.90 × 10−8
|
8 |
| MF |
GO:0005524 ATP binding |
4.05 × 10−6
|
21 |
| MF |
GO:0003777 microtubule motor activity |
9.37 × 10−7
|
7 |
| MF |
GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed |
9.68 × 10−7
|
5 |
| MF |
GO:0004222 metalloendopeptidase activity |
2.71 × 10−3
|
5 |
| MF |
GO:0061630 ubiquitin protein ligase activity |
9.04 × 10−3
|
5 |
| MF |
GO:0016887 ATPase activity |
1.74 × 10−2
|
4 |
| B.Downregulated |
| Category |
Term/gene function |
P-value |
Count |
| BP |
GO:0043547 positive regulation of GTPase activity |
4.74 × 10−5
|
24 |
| BP |
GO:0001525 angiogenesis |
3.53 × 10−6
|
16 |
| BP |
GO:0007155 cell adhesion |
7.85 × 10−3
|
16 |
| BP |
GO:0008285 negative regulation of cell proliferation |
5.18 × 10−3
|
15 |
| BP |
GO:0035556 intracellular signal transduction |
6.03 × 10−3
|
15 |
| BP |
GO:0006508 proteolysis |
3.31 × 10−2
|
15 |
| CC |
GO:0016021 integral component of membrane |
2.43 × 10−3
|
110 |
| CC |
GO:0005886 plasma membrane |
1.19 × 10−6
|
106 |
| CC |
GO:0070062 extracellular exosome |
4.76 × 10−2
|
59 |
| CC |
GO:0005887 integral component of plasma membrane |
3.25 × 10−7
|
51 |
| CC |
GO:0005576 extracellular region |
2.17 × 10−4
|
47 |
| CC |
GO:0005615 extracellular space |
3.39 × 10−3
|
37 |
| MF |
GO:0005509 calcium ion binding |
5.39 × 10−4
|
25 |
| MF |
GO:0005088 Ras guanyl-nucleotide exchange factor activity |
9.62 × 10−5
|
10 |
| MF |
GO:0008201 heparin binding |
1.11 × 10−3
|
10 |
| MF |
GO:0005215 transporter activity |
1.61 × 10−2
|
9 |
| MF |
GO:0016887 ATPase activity |
2.79 × 10−2
|
8 |
| MF |
GO:0004871 signal transducer activity |
4.57 × 10−2
|
8 |
