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. 2019 Nov 14;14(11):e0225080. doi: 10.1371/journal.pone.0225080

Table 5. Hub genes and rank of degrees.

Gene symbol Description Feature Degree
BUB1 BUBI mitotic checkpoint serine/threonine kinase up 52
CCNB1 Cyclin B1 up 51
MAD2L1 Mitotic arrest deficient 2 like 1 up 50
TOP2A DNA topoisomerase 2-alpha up 49
KIF11 Kinesin family member 11 up 49
CDC20 Cell divison cycle 20 up 49
BUB1B BUBI mitotic checkpoint serine/threonine kinase B up 49
PBK PDZ binding kinase up 48
ASPM Abnormal spindle microtubule assembly up 48
NCAPG Non-SMC condensin I complex subunit G up 48
CENPF Centromere protein F up 48
TTK TTK protein kinase up 48
AURKB Aurora kinase B up 48