. Author manuscript; available in PMC: 2019 Nov 14.

Published in final edited form as: JACC Cardiovasc Imaging. 2015 Jan 7;8(2):121–130. doi: 10.1016/j.jcmg.2014.10.009

Table 2.

Relationship between Hematopoietic Tissue Activity and Inflammatory Biomarkers

	Bone marrow FDG Uptake		Spleen FDG Uptake
	correlation coefficient	p value	correlation coefficient	p value
Serum Biomarkers
CRP	0.62	0.002	0.44	0.04
TNF	0.19	0.46	0.39	0.44
IL1-beta	0.43	0.09	−0.37	0.47
Gene Expression in Leukocytes
CD36	0.05	0.85	0.51	0.03
MSR-1	0.53	0.02	0.48	0.04
S100A9	0.15	0.54	0.59	0.01
TLR-2	0.19	0.45	0.45	0.06

Bone marrow and spleen FDG uptakes are analyzed as standardized uptake value (SUV). Correlation coefficients represent Spearman ρ. Correlations are assessed in the entire population (n=44) including both post-ACS and control subjects. In analyses that were limited to the sub-groups, we did not observe significant correlations except for between S100A9 expression and splenic activity in the control group (ρ=0.8, p=0.02).

CRP, C-reactive protein; TNF, tumor necrosis factor; MSR-1, Macrophage Scavenger Receptor 1; TLR-2, toll-like receptor 2