Table 2.
Bone marrow FDG Uptake | Spleen FDG Uptake | |||
---|---|---|---|---|
correlation coefficient | p value | correlation coefficient | p value | |
Serum Biomarkers | ||||
CRP | 0.62 | 0.002 | 0.44 | 0.04 |
TNF | 0.19 | 0.46 | 0.39 | 0.44 |
IL1-beta | 0.43 | 0.09 | −0.37 | 0.47 |
Gene Expression in Leukocytes | ||||
CD36 | 0.05 | 0.85 | 0.51 | 0.03 |
MSR-1 | 0.53 | 0.02 | 0.48 | 0.04 |
S100A9 | 0.15 | 0.54 | 0.59 | 0.01 |
TLR-2 | 0.19 | 0.45 | 0.45 | 0.06 |
Bone marrow and spleen FDG uptakes are analyzed as standardized uptake value (SUV). Correlation coefficients represent Spearman ρ. Correlations are assessed in the entire population (n=44) including both post-ACS and control subjects. In analyses that were limited to the sub-groups, we did not observe significant correlations except for between S100A9 expression and splenic activity in the control group (ρ=0.8, p=0.02).
CRP, C-reactive protein; TNF, tumor necrosis factor; MSR-1, Macrophage Scavenger Receptor 1; TLR-2, toll-like receptor 2