TABLE 1.
Patient Characteristics
| Characteristic | Overall | 18F-FET-PET Volume ≤ 4.3 cm3 | 18F-FET-PET Volume > 4.3 cm3 | P value |
|---|---|---|---|---|
| Number of cases | 31 | 11 | 20 | – |
| Age in years | 66.8 (51.2 - 71.5) | 55.1 (41.74 - 68.67) | 67.2 (57.99 - 74.33) | .064† |
| Female/Male (n,%) | 18/13 (58.1%/41.9%) | 7/4 (63.6%/36.4%) | 11/9 (55%/45%) | .718# |
| MGMT Methylation (n,%) | 18 (58.1%) | 8 (72.7%) | 10 (55.6%) | .276# |
| IDH Mutation (n,%) | 2 (6.5%) | 2 (18.2%) | 0 (0%) | .118# |
| Residual Fluorescence (n,%) | 18 (58%) | 2 (18.2%) | 16 (80%) | .002# |
| No Residual Fluorescence (n,%) | 13 (41.9%) | 9 (81.8%) | 4 (20%) | |
| Early Postoperative Gd+ Volume in cm3 | 0 (0 - 1.1) | 0 (0 - 0.02) | 0.51 (0.04 - 1.99) | .005† |
| CRET (%) | 18 (58%) | 11 (100%) | 7 (35%) | < .001# |
| Early Postoperative 18F-FET-PET Volume in cm3 | 7.3 (2.2 - 25.3) | 1.07 (0.22 - 2.91) | 13.98 (7.46 - 28.55) | – |
| Surgically acquired permanent motor or language deficit (n,%) | 1 (3%) | 0 (0%) | 1 (5%) | > .99# |
Data are presented median (25% quantile-75% quantile) or frequencies (percentages). Statistically noticeable differences between 18F-FET-PET Volume ≤ 4.3 cm3 and > 4.3 cm3 are marked in bold (P ≤ .05). CRET complete resection of enhancing tumor; Gd+ gadolinium contrast enhancing tumor; IDH isocitrate dehydrogenase; IQR interquartile range; MGMT O6-methylguanine-DNA methyltransferase; †Mann–Whitney U test, #Fisher's exact.