FIGURE 1.

Change in total mortality risk associated with increments of calorie intake from specific types of fat in the Nurses’ Health Study and Health Professionals Follow-Up Study. Multivariable HRs are shown for total mortality associated with replacing the percentage of energy from total carbohydrates with the same energy from specific types of fat (P-trend < 0.001 for all), adjusted for age, race, marital status, BMI, physical activity, smoking status, alcohol consumption, multivitamin use, vitamin E supplement use, current aspirin use, family history of myocardial infarction, family history of diabetes, family history of cancer, history of hypertension, history of hypercholesterolemia, intakes of total energy and dietary cholesterol, percentage of energy intake from dietary protein, menopausal status and hormone use in women, and percentage of energy from the remaining specific types of fat. Reproduced with permission from reference 22.