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. 2019 Mar 5;111(11):1186–1191. doi: 10.1093/jnci/djz030

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Figure 1. — Survival and progression-free survival (PFS) benefits in the trial comparing ipilimumab plus dacarbazine vs placebo plus dacarbazine in metastatic melanoma. A) Kaplan-Meier estimates of PFS functions over time. B) Net PFS benefit of at least $m$ months. C) Kaplan-Meier estimates of overall survival functions over time. D) Net survival benefit of at least $m$ months. $Δ$ = net benefit; CI = 95% confidence interval; OS = overall survival.