TABLE 5.
Symptomatic Outcomes Following Definitive GKRS for Vestibular Schwannomas
| Post-treatment Symptoms | % (Frequency): Transient symptoms | % (Frequency): Persistent symptoms | % (Frequency): Total symptoms (Persistent or transient) |
|---|---|---|---|
| Hearing loss (HL) | |||
| New-onset HL | 14.3% (3/21) | 23.8% (5/21) | 38.1% (8/21) |
| Worsening of prior HL | 3.9% (8/206) | 50/206 (24.2%) | 28.2% (58/206) |
| Improvement of prior HL | — | — | 1.0% (2/206) |
| FND | |||
| New-onset FND | 4.6% (10/217) | 4.1% (9/217) | 8.8% (19/217) |
| Worsening of prior FND | 0.0% (0/10) | 0.0% (0/10) | 0.0% (0/10) |
| Improvement of prior FND | — | — | 90% (9/10) |
| TND | |||
| New-onset TND | 2.5% (5/203) | 4.4% (9/203) | 6.9% (14/203) |
| Worsening of prior TND | (0.0%) 0/24 | 4.2% (1/24) | 4.2% (1/24) |
| Improvement of prior TND | — | — | 79.2% (19/24) |
| Vertigo/dizziness/disequilibrium (V/D/D) | |||
| New-onset V/D/D | 10.8% (10/93) | 16.1% (15/93) | 26.9% (25/93) |
| Worsening of prior V/D/D | 6.0% (8/134) | 6.0% (8/134) | 11.9% (16/134) |
| Improvement of prior V/D/D | — | — | 62.7% (84/134) |
| Tinnitus | |||
| New-onset tinnitus | 1.9% (2/104) | 5.8% (6/104) | 7.7% (8/104) |
| Worsening of prior tinnitus | 0.8% (1/123) | 5.7% (7/123) | 6.5% (8/123) |
| Improvement of prior tinnitus | — | — | 83.7% (103/123) |
| Lateralized headache (HA) | |||
| New-onset HA | 1.0% (2/208) | 2.4% (5/208) | 7/208 (3.4%) |
| Worsening of prior HA | 0.0% (0/19) | 0.0% (0/19) | 0/19 (0.0%) |
| Improvement of prior HA | — | — | 18/19 (94.7%) |