. 2019 Nov 14;9:16820. doi: 10.1038/s41598-019-53287-y

Table 2.

OPLS-DA parameters and permutation test for distinguishing GD and LCKD groups.

Group	OPLS-DA				p-value^b
Group	Components^a	Q²	R²	Q²/R²	p-value^b
GD-LCKD
Week 0–0	5	0.470	0.943	0.50	0.055
Week 2–2	1	0.555	0.964	0.58	0.024
Week 4–4	3	0.608	0.938	0.65	0.057
GD-GD
Week 0–2	6	0.554	0.998	0.60	0.129
Week 0–4	5	0.470	1.000	0.47	0.181
Week 2–4	3	0.569	0.999	0.57	0.174
LCKD-LCKD
Week 0–2	6	0.780	1.000	0.78	0.120
Week 0–4	—	—	—	—	—
Week 2–4	7	0.649	1.000	0.65	0.525

^aThe number of components based on Q² indicates the best classifier of OPLS-DA using a 7-fold cross-validation method.

^bp-value was determined by CV-ANOVA of OPLS-DA in SIMCA 14.1. p < 0.05 was considered significant.

CV-ANOVA, cross-validated analysis of variance; OPLS-DA, orthogonal partial least squares discriminant analysis; Q², predictive capability; R², goodness of fit. OPLS-DA not performed was shown as “—”.