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. 2019 Nov 8;10:2564. doi: 10.3389/fimmu.2019.02564

Figure 7.

Figure 7

Changes of body weight and virus titers in skeletal muscle of BALB/c suckling mice. (A) One-day-old suckling BALB/c mice from mothers immunized with (25, 50, 50 μg) EVP1, CVP1, EVP1+CVP1 (1:1), or BSA were i.p. injected with 200 LD50 EV71. The body weight changes were monitored every day. (B) One-day-old suckling BALB/c mice from mothers immunized with (25, 50, 50 μg) EVP1, CVP1, EVP1+CVP1 (1:1), or BSA were i.p. injected with 150 LD50 CB3. The body weight changes were monitored every day. (C) One-day-old suckling BALB/c mice from mothers immunized with (25, 50, 50 μg) EVP1, CVP1, EVP1+CVP1 (1:1), or BSA were i.p. injected with 200 LD50 EV71. Skeletal muscles of suckling mice were removed and virus titers were detected at days 1, 3, 5, and 7. (D) One-day-old suckling BALB/c mice from mothers immunized with (25, 50, 50 μg) EVP1, CVP1, EVP1+CVP1 (1:1), or BSA were i.p. injected with 150 LD50 CB3. Skeletal muscles of suckling mice were removed and virus titers were detected at days 1, 3, 5, and 7.