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. 2019 Nov 14;9:16761. doi: 10.1038/s41598-019-53384-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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N-Glycan analysis of immunoglobulins (Igs). N-Glycan profiling in Igs was not consistent with that of whole serum N-glycan profiling. The Igs-related N-glycans of m/z 1871 (A), 2337 (B), and 2744 (C) were significantly decreased in the CRPC patients than that of non-CPRC patients. There was no significant difference in the m/z 2890 (D), 3049 (E), 3109 (F), and 3195 (G) between the CRPC and non-CPRC patients. The N-glycans of m/z 3414, and m/z 3719 were not detected on Igs.