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. 2019 Nov 14;9:16802. doi: 10.1038/s41598-019-53191-5

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Significant correlations between levels of TIPRL, LC3 and CD133 in liver cancers. (a–c) The statistically significant associations between levels of TIPRL, LC3 and CD133 in each grade of liver cancers were determined by the Spearman correlation. Each dot indicates a single patient. (d) The representative images were selected from each grade of human liver cancer tissues that were stained with indicated antibodies. DAPI was used for nucleus staining, and scar bar, 100 μm. (e) Quantitative analyses of TIPRL, LC3 and CD133 were conducted according to each grade of liver cancers. (n), the number of samples is indicated.