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. 2019 Nov 14;7:35. doi: 10.1038/s41413-019-0076-5

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — BMSCs^adipo and BMSCs^osteo exhibit significant differences in their metabolite composition. Global metabolic analyses of intracellular metabolites in basal conditions in BMSCs^adipo and BMSCs^osteo using liquid chromatography–mass spectrometry (LC–MS). a Heat map of all intracellular metabolites that are differentially expressed between BMSCs^adipo and BMSCs^osteo under basal conditions; b important features that are differentially expressed in BMSCs^adipo and BMSCs^osteo; c metabolites differentially enriched in BMSCs^adipo versus BMSCs^osteo such as glycerophospholipids, especially phosphocholine and CPD-choline, glutathione, xanthine, and hypoxanthine. Data are presented as the mean ± SEM from three independent experiments. (n = 3) (*P < 0.05, **P < 0.01, ***P < 0.001: BMSCs^adipo vs BMSCs^osteo, two-tailed unpaired Student’s t test)