Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Nov 14;7:35. doi: 10.1038/s41413-019-0076-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — PTH affects the adipogenic potential of BMSCs^adipo progenitors. Evaluation of PTH treatment on AD differentiation potential in BMSCs^adipo and BMSCs^osteo. a Representative pictures and evaluation of Nile Red staining in BMSCs^adipo differentiated in adipogenic conditions (AD) and after chronic (D10) PTH treatment, (scale bar 100 μm); b gene expression of adipocytic and insulin signaling-related genes such as Pparγ2, Fsp27, and Irs1 after chronic PTH treatment; c gene expression of PTH-responsive genes such as Bmp4, Igf1, and Igfr1 after chronic PTH treatment; data are presented as the mean of the fold change (F.C.) over undifferentiated cells ± SEM, (n = 3) d representative western blot and densitometry of insulin-stimulated (100 nmol·L^–1, 15 min) phosphorylation of AKT (p-S473AKT) and total AKT and gene expression of Insr in BMSCs^adipo treated with PTH 100 nmol·L^–1; (n = 3); e glycolytic potential of BMSCs^adipo and ATP production after 24 h of PTH treatment (n = 3); data are presented as the mean ± SEM (*P < 0.05, **P < 0.01; ***P < 0.001: BMSCs^adipo vs BMSCs^osteo, two-tailed unpaired Student’s t test)