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. 2019 Nov 14;9:16872. doi: 10.1038/s41598-019-53410-z

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Structural insight into the interaction of 5′r(CCGCAGCGG)3′ with CP13 using NMR spectroscopy. One dimensional proton spectra of RNA as a function of increasing concentration of CP13 showing (a) base region (b) NMR titration of CP13 with increasing concentration of RNA (c–d) Two dimensional NMR spectroscopy of 5′r(CCGCAGCGG)3′ with CP13 at 298 K, at D/N ratios of (c) D/N = 0.0 (d) D/N = 2.0 (e–f) Docked structure of RNA with compounds (e) CP2 (f) CP6 (g) CP13