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. 2019 Nov 8;7:289. doi: 10.3389/fbioe.2019.00289

Figure 11.

Figure 11

Encapsulation of PTE within bacterial OMVsThe directed packaging of PTE within bacterial OMVs conveys improved stability to the enzymes allowing it to maintain activity over several common storage conditions such as freezing at −80°C and lyophilization and rehydration. Unlike some synthetic liposome formulations, bacterial OMVs maintain their morphology following lyophilization and rehydration (middle panel, b). Encapsulation within the vesicles also allowed the enzyme to be stored for up to 14 days over a range of conditions while maintain a high level of enzyme activity compared to controls. This figure is a combination of data sets presented in Alves et al. (2015, 2016). Both figure reproduced with permission.