Table 4.
Varicella-related complications (VRCs) in immunocompromised and immunocompetent children hospitalized in Bavaria between January 2005 and December 2011
| VRC in immunocompromised patients | VRC in immunocompetent patients | p valuea | |
|---|---|---|---|
| N = 93 | N = 1170 | ||
| n (%) | n (%) | ||
| At least one complication | 48 (51.6) | 906 (77.4) | < 0.001*** |
| Gastrointestinal complication | 15 (16.1) | 324 (27.7) | 0.015* |
| Neurologic | 4 (4.3) | 224 (19.1) | < 0.001*** |
| Skin | 7 (7.5) | 171 (14.6) | 0.063 |
| URT, ENT, eye | 5 (5.4) | 185 (15.8) | 0.004** |
| LRT | 7 (7.5) | 153 (13.1) | 0.145 |
| Hematologic complications | 19 (20.4) | 25 (2.1) | < 0.001*** |
| Systemic bacterial | 6 (6.5) | 20 (1.7) | 0.009** |
| Coagulation and sequelae | 5 (5.4) | 16 (1.4) | 0.015* |
| Reactive arthritis | 1 (1.1) | 8 (0.7) | 0.499 |
| Other complications | 22 (23.7) | 236 (20.2) | 0.424 |
Patients could appear in more than one complication category, but only once per category
***Significant at 0.1% level, **significant at 1% level, *significant at 5% level
aTwo-sided p value for comparison of complications in immunocompromised and immunocompetent children hospitalized with varicella; Pearson’s Chi2 or Fisher’s exact test as appropriate