Table 2. Uni- and multi-variable analysis for obstructive CAD (≥ 50% DS), SIS > 4, and SSS >8 based on findings on coronary computed tomographic angiography.
| Variables | Obstructive CAD (≥ 50% DS) | SISa > 4 | SSSb > 8 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Univariable | Multivariable | Univariable | Multivariable | Univariable | Multivariable | |||||||
| OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
| Age ≥ 70 yr | 6.2 (2.5–15.3) | < 0.001 | 6.2 (2.6–14.7) | 0.000 | 3.3 (1.3–8.2) | 0.010 | 3.0 (1.2–7.1) | 0.015 | 4.8 (1.5–15.4) | 0.008 | 3.8 (1.3–11.4) | 0.015 |
| Gender (men) | 5.8 (1.8–19.3) | 0.004 | 4.3 (1.4–13.3) | 0.012 | 1.8 (0.6–5.6) | 0.276 | 2.2 (0.9–5.6) | 0.089 | 3.2 (0.7–14.2) | 0.119 | - | - |
| Hypertension | 1.4 (0.6–3.3) | 0.499 | - | - | 2.5 (1.0–6.4) | 0.062 | - | - | 2.2 (0.7–7.0) | 0.204 | - | - |
| DM | 5.7 (2.3–14.3) | 0.000 | 6.2 (2.5–15.1) | < 0.001 | 2.3 (0.9–5.8) | 0.084 | 2.4 (1.0–6.1) | 0.060 | 3.4 (1.1–10.3) | 0.028 | 4.0 (1.4–11.8) | 0.011 |
| Dyslipidemia | 1.6 (0.7–3.8) | 0.289 | - | - | 1.4 (0.6–3.5) | 0.423 | - | - | 1.4 (0.4–4.1) | 0.595 | - | - |
| Current smoker | 0.4 (0.1–1.3) | 0.123 | - | - | 1.2 (0.4–4.1) | 0.716 | - | - | 0.6 (0.1–3.0) | 0.559 | - | - |
| Obesity | 0.9 (0.3–2.3) | 0.809 | - | - | 0.9 (0.3–2.3) | 0.747 | - | - | 1.6 (0.5–5.2) | 0.406 | - | - |
| RAO | 3.2 (1.2–8.6) | 0.019 | 3.0 (1.2–7.6) | 0.024 | 2.6 (1.0–6.8) | 0.052 | 2.8 (1.1–7.0) | 0.031 | 3.5 (1.1–11.3) | 0.036 | 3.4 (1.1–10.3) | 0.030 |
P < 0.05 was deemed to indicate clinical significance, values in boldface are statistically significant.
CAD = coronary artery disease, DS = diameter stenosis, SIS = segment-involvement score, SSS = segment-stenosis score, OR = odds ratio, CI = confidence interval, DM = diabetes mellitus, RAO = retinal artery occlusion.
aSIS, total number of coronary artery segments with exhibiting plaque, ranging from 0 to 15; bSSS, sum of the score of each segment graded as 0–2, ranging from 0 to 30 (0, no CAP; 1, < 50% DS; 2, ≥ 50% DS).