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. 2019 Nov 14;85(23):e01438-19. doi: 10.1128/AEM.01438-19

FIG 2.

FIG 2

Antagonistic events of env-Ps against CF-Ps. A competition plate assay was used to determine antagonistic activity (inset). A total of 471 env-Ps were competed against 65 CF-Ps that resulted in 30,615 individual competitions. Of the 1,530 antagonistic events observed, activity originated from 579 U.S. (purple bars), 359 German (dark-blue bars), and 592 Hungarian (light-blue bars) env-Ps that inhibited the growth of nine Achromobacter, 19 Burkholderia, 31 P. aeruginosa, and three Stenotrophomonas strains. Black arrows indicate activity by three antagonistic strains. Only one Burkholderia strain and one P. aeruginosa strain were not inhibited by any env-P. P. aeruginosa strains were tested for susceptibility against eight antibiotics using the Kirby-Bauer disk assay. Numbers above the antagonistic bar data represent the number of drugs a particular pathogen resists, indicated in Table 1. Linear regression analysis showed that the number of antagonistic events to a pathogen was inversely related to antibiotic resistance.