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. 2019 Nov 14;9:16849. doi: 10.1038/s41598-019-52564-0

Table 2.

Annual HCV–associated cost in Spain’s prisons for years 2019, 2020, 2025, 2030, 2035, 2040, 2045, and 2050 under status quo and different strategies for scaling-up treatment to all prisons.

Cost Type Strategy 2019 2020 2025 2030 2035 2040 2045 2050
Screening (€) Status quo 7,907 5,876 6,868 2,698 2,150 1,925 1,265 802
Strategy 1 7,907 13,440 13,380 6,024 4,118 2,550 1,929 687
Strategy 2 7,907 9,658 12,295 6,641 4,564 2,782 1,532 689
Strategy 3 7,907 14,412 13,733 6,960 4,478 2,624 1,732 1,205
Strategy 4 7,907 14,695 14,814 5,821 4,302 2,236 1,730 803
Treatment (€) Status quo 8.1 M 7.9 M 7 M 5.9 M 5.1 M 4.3 M 3.7 M 3.1 M
Strategy 1 93.1 M 91.2 M 80 M 40 M 23.3 M 13 M 8.4 M 5.8 M
Strategy 2 93 M 90.5 M 80.3 M 39.6 M 23.4 M 12.8 M 8.3 M 5.8 M
Strategy 3 315.4 M 118.4 M 67.9 M 37.8 M 22.9 M 13 M 8.3 M 5.8 M
Strategy 4 404.6 M 180.2 M 81.7 M 44.7 M 26.2 M 14.7 M 8.9 M 6.1 M
Disease management (€) Status quo 3.7 M 3.5 M 2.8 M 2 M 1.5 M 0.9 M 0.6 M 0.4 M
Strategy 1 3.1 M 2.6 M 1.4 M 0.7 M 0.4 M 0.2 M 0.2 M 0.1 M
Strategy 2 3.2 M 2.7 M 1.4 M 0.7 M 0.4 M 0.2 M 0.2 M 0.1 M
Strategy 3 2.1 M 1.7 M 1.1 M 0.6 M 0.4 M 0.2 M 0.2 M 0.1 M
Strategy 4 1.9 M 1.5 M 0.9 M 0.5 M 0.3 M 0.2 M 0.1 M 0.1 M
Total (€) Status quo 11.8 M 11.5 M 9.8 M 7.9 M 6.6 M 5.2 M 4.3 M 3.5 M
Strategy 1 96.2 M 93.8 M 81.4 M 40.7 M 23.7 M 13.2 M 8.5 M 5.9 M
Strategy 2 96.2 M 93.3 M 81.8 M 40.3 M 23.9 M 13 M 8.5 M 5.9 M
Strategy 3 317.5 M 120.2 M 69.1 M 38.4 M 23.4 M 13.2 M 8.4 M 5.9 M
Strategy 4 406.5 M 181.7 M 82.7 M 45.2 M 26.5 M 14.9 M 9 M 6.2 M

Under status quo, 160 inmates were treated regardless of their fibrosis stages or prisons’ HCV prevalence. Strategy 1 prioritizes inmates by their fibrosis stages (fibrosis scores F4, F3, F2, F1, and F0) with a treatment capacity of 2,000/year, irrespective of the prison or region. Strategy 2 prioritizes prisons by their HCV prevalence with a treatment capacity of 2,000/year, irrespective of fibrosis stages. Strategy 3 considers unlimited capacity. In Strategies 1–3, only those sentenced with more than six months are eligible for treatment. Strategy 4 considers unlimited treatment capacity and assumed everyone, irrespective of their sentence length, is eligible for treatment.