Fig. 4. We used the RDoC “Social Processing: Understanding Mental States” domain dimension matrix to organize our results across different levels of biology and literature.

DLPFC dorsal lateral prefrontal cortex, Pre-SMA pre-somatosensory area, OTJ occipital temporal junction, TPJ temporoparietal junction, Ca+ calcium, positive charge. ¹Results were estimated directly in this study. ²Results were found using MNI coordinates that overlap spatially with those found in the fMRI literature, including the Yeo 7 networks and Neurosynth meta-analytic database. ³Results use the Allen Brain Atlas to visualize expression of PGC MDD-associated genes